Evaluation the Hematopoietic Potential of Wheat Grass Tablets in Transfusion Dependent Thalassemia with Beta Mutations

Abstract

B-thalassemia results from decrease or absence of beta globin production which end with abnormal levels hemoglobin types in adults. Wheat grass has been utilized for different medicinal purposes and due to the great benefits of wheat grass in hemoglobin deficiency disorder is commonly known as green blood. In this study, data collected from 88 patient with major beta-thalassemia (MBT) to evaluate the hematopoietic effect of wheat grass. The patient randomly allocated in two groups (wheat grass treated group (WG) and case control group). Regular blood transfusion, folic acid, and iron chelation therapy was received continuously during the study for both groups.                 

Hemoglobin levels Hg, transfusions number, and ferritin levels assessed before the study, and after 3, 6 months. Significant elevation in serum Hg reported in WG treated group versus case control group, transfusions number and ferritin levels was significantly lower in in WG treated group versus case control group while no difference seen in the measurement of liver and spleen dimensional.                                                                                                          

Depended on the presented information from the study course, wheat grass tablets presented a promising role in transfusion dependent thalassemia through its action to enhance hematological measurements.